Our services include both Standard and Modified peptide synthesis:
Standard Peptide Synthesis
Automated custom synthesis of peptides on a scale of 1-500 mg, purification (standard-purities: 80% or 95%) and analysis of all products by HPLC and mass spectrometry.
Modified Peptide Synthesis
- Incorporation of residues with modified aliphatic or aromatic side-chains, e.g. methyl-, dimethyl-, and trimethyllysine, methyl- and dimethylarginine (sym. or asym.), hydroxyproline, citrulline, selenocysteine and methionine
- Phosphorylation at Tyr, Ser and Thr
- Glycosylated peptides with Asn(GlcNAc), Ser/Thr(GalNAc, TF, etc.)
- Peptides with 2D, 13C and 15N labeled amino acids
- Depsipeptides
- Cyclic peptides (via backbone or disulfide bridges)
N- and C-terminale Derivatization
- Biotinylation
- Incorporation of hydrophobic or hydrophilic (PEG)-spacer
- Acetyl-, formyl- and palmitoyl-peptides
- Peptide hydrazides, peptidehydroxamates and alkylated peptide amides
- Selective linker for peptide conjugates (chloro- or bromoacetyl-)
- Incorporation of Cys(Pys/Npys) for synthesis of peptide conjugates or asymmetric cystine peptides
Fluorescence labeling
- Labeling with fluorescein, rhodamine, and coumarine derivatives (e.g. FITC, TAMRA and AMC)
- Peptide labeling with single isomer DYOMICS-dyes (spectral range 400-800nm), see www.dyomics.com
- Fluorescence lifetime markers
- FRET-systems (Abz/Tyr(NO2), Dnp/AMC, Dabcyl/Edans, Dabsyl/ Lucifer Yellow among others)
- Rhodamin 110 peptides (substituated sym. or asym.)
Custom Peptide Synthesis – Overview and Prices (PDF, not yet available)
For questions or a personal consultation, do not hesitate to contact us at the following telephone number or e-mail address:
Telephone: +49 30-9489-2201
E-mail: tech(at)empbiotech.com
