Product number: AF-0105

5-Carboxyfluorescein NHS ester, single isomer (5-FAM-SE)

Amine-reactive fluorescein dye marker for fluorescence labeling, especially for labeling of biomolecules (Abs: 495 nm, Em: 519 nm).

Ready for shipping

Excitation [nm]:	496
Name:	4-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-isophthalic acid 3-(2,5-dioxo-pyrrolidin-1-yl) ester

This single isomer amine-reactive derivatization reagent may be used for covalent labeling of proteins and alkylamino modified nucleic acids.

Fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser, making it the predominant fluorophore for confocal laser scanning microscopy and flow cytometry applications. It has a relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.

Importantly, protein-fluorescein conjugates are not inordinately susceptible to precipitation.

English Information
German Information

Hazard Classifications

Skin irritation, Category 2 (Skin Irrit. 2)
Eye irritation, Category 2 (Eye Irrit. 2)
Specific target organ toxicity - single exposure, Category 3 (STOT SE 3)

Hazard Statements

H315	Causes skin irritation.
H319	Causes serious eye irritation.
H335	May cause respiratory irritation.

Downloads

Material safety data sheet

Sicherheitsdatenblatt

Precautionairy Statements

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: Wash with plenty of water/…
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Signal Word

Warning

WGK

WGK 3

Storage Class Code

13 - Non-flammable solids in non-flammable package

ADR, RID (road and railroad)

Not dangerous goods

IATA-DGR (transport by air)

Not dangerous goods

IMDG-Code (transport by sea)

Not dangerous goods

Gefahreneinstufungen

Ätz-/Reizwirkung auf die Haut, Kategorie 2 (Skin Irrit. 2)
Schwere Augenschädigung/Augenreizung, Kategorie 2 (Eye Irrit. 2)
Spezifische Zielorgan-Toxizität (einmalige Exposition), Kategorie 3 (STOT SE 3)

Downloads

Material safety data sheet

Sicherheitsdatenblatt

Gefahrenhinweise - H-Sätze

H315	Verursacht Hautreizungen.
H319	Verursacht schwere Augenreizung.
H335	Kann die Atemwege reizen.

Sicherheitshinweise - P-Sätze

P261	Einatmen von Staub/Rauch/Gas/Nebel/Dampf/Aerosol vermeiden.
P262	Nicht in die Augen, auf die Haut oder auf die Kleidung gelangen lassen.
P280	Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz/Gehörschutz/… tragen.
P302+P352	BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/… waschen.
P305+P351+P338	BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.